The Holley's self-learning on the fueling is like the stock PCM on steroids, it's has what is basically a short term fuel learn and a long term. If it sees a part of the fuel map that needs constant adjustment it will update the learn table and you can just apply it to the base map and go again. It learns so quick that a lot of people are saying you don't even need a flex fuel sensor but I'm using one anyway. As long as your base fuel map is pretty smooth it should be able to dial things in pretty much perfectly for fueling.
For cranking it's going to need about 2 revolutions before it will fire because it has to wait for the cam signal, but if it's sitting there kinda half-firing you'll probably want to make a few changes. I feel like mine is relatively dialed in on my GP at this point but I do want to work on the cold startup to see if I can make it behave more like my truck does haha. Also keep in mind that if you're running E85 it will need even more cranking fuel when it's cold.
This is what mine looks like in my GP and I haven't had a day yet where it didn't fire up right away.
About the crank trigger, there's a lot of people running V8's using the MSD flying magnet setup which is only 4 crank triggers and they're seeming to have no problem with the low resolution from it. I think the idle timing has to suffer a little bit if you ask me but it works pretty well otherwise.
Just curious. Would there be any benefit to switching to a hall effect sensor and trigger wheel with more teeth? I saw someone complaining about that on another forum which is the only reason I even questioned. If so, it would be slick if someone came up with a replacement wheel for stock sensors and balancers.
Funny you should mention this because I've been working on making something like that myself the last few weeks lol
This is an early design that has a couple kinks but I think I'm getting close to something I could sell if people are interested.
If this works out you wouldn't need a cam sensor to get the engine to fire if you use batch injection I believe since it has a missing tooth. Both are supported by the Holley and then with our cranks if there's an issue and you want to go back to the 3x signal you'd still be able to do that.