Oh yes... They can. These fuckers will climb up anything (trees, hacienda's, other structures), get on your roof, then with their claws pull up you flashing around bathroom vents, get in there, nest, then you're really fucked when a momma gives birth.
Years back, around 3am, all the sudden I'd hear this thump, thump, thump across our roof, waking the kids, go out and sure as shit, there is a fat bastard racoon on the roof. I'd shoot bastard with my pellet gun to get him off the roof.
Well, turns out my neighbor across the way was also having issues with him/them (they live in the fucking sewers). So we commiserated, and started to control the raccoon population ourselves. He'd just shoot them with his .22. If I had an issue, I'd flash the bat signal (my big LED light), at his front window and he'd come out and he'd shoot the damn thing. Thing is, you gotta get them right between the eyes, otherwise they have too much "fluff" to really make much of a difference. Which isn't hard to do because they're fucking stupid too. Shine the light at them and they stare right at it. BAM! Done.