During a panel today at PSX 2016, creative director Shaun Escayg confirmed that The Lost Legacy will take place after Uncharted 4: A Thief's End, and the section shown during the reveal was taken from the beginning of the game.
The Lost Legacy will be set in India, and as such, writer Josh Scherr said the studio took a "deep dive" into Hinduism and the mythology tied to the region when crafting the story. Game director Kurt Margenau also chimed in to note the setting shown in the reveal footage won't be the only locale Chloe will explore.
Escayg emphasized that The Lost Legacy is very much Chloe's story. While it will be tonally different from Drake's adventures, it will still fit within the context of the Uncharted universe, with Chloe on a quest for a piece of treasure called the Tusk of Ganesha.
As far as gameplay is concerned, Margenau said Chloe will have her "own fighting personality," and won't be as "brawly" as Nathan Drake. Margenau also discussed the game's length, saying it will be "longer than [The Last of Us] Left Behind but shorter than Uncharted 4."
Additionally, Margenau said fans can expect the same "wide-linear" level design seen in Uncharted 4. In fact, The Lost Legacy is "going even a little more wide," with Margenau suggesting there will be plenty of driving, thanks to Chloe's skills behind the wheel.